San Francisco 49ers
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-5.5
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Los Angeles Chargers
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Sun, Aug 22 - 7:30p ET   |   NFLN   |   SoFi Stadium
By Landon Smith

San Francisco 49ers vs Los Angeles Chargers 8/22/21 NFL Football Pre Season Week 2 Matchups

San Francisco 49ers Will Face Los Angeles Chargers in a NFL Football Pre Season Week 2 Matchups and Head to Head from the SoFi Stadium, Inglewood, CA, on Sunday, August 22, 2021.

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San Francisco 49ers at Los Angeles Chargers NFL Football Pre Season Week 2 Betting Matchups, Trends and Head to Head, Match on Sunday, August 22, 2021, at the SoFi Stadium, Inglewood, CA.

San Francisco 49ers vs Los Angeles Chargers Betting Matchups

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By Landon Smith, on 7:30p ET